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Hydroxyzine Hydrochloride Tablets USP, 25 mg and 50 mg also contain D&C Yellow No. 10 and FD&C Blue No. 2.

Both hydroxyzine and cetirizine act as antihistamines.


Atarax has a sedative and anxiolitic effect. It is an antihistamine with anticholinergic and sedative properties used to treat allergy. It positively affects cognitive abilities, improves memory and attention. The medication does not cause psychological dependence and addiction. It relaxes smooth muscles, has a bronchodilator and analgetic effect as well as moderately inhibits gastric secretion, it may be used as antiemetic and myorelaxant. Hydroxyzine reduces itching from hives, eczema, dermatitis, etc. After ingestion Hydroxyzine is converted to its active form named cetirizine (Zyrtec).

Hydroxyzine hydrochloride is designated chemically as 2-<>-<>-(p-Chloro-?-phenylbenzyl)-1-piperazinyl]ethoxy] ethanol dihydrochloride.

Hydroxyzine hydrochloride structural formula illustration


C21H27CIN2022HCI M.W. 447.83

Hydroxyzine hydrochloride occurs as a white, odorless powder which is very soluble in water.

Hydroxyzine Hydrochloride Tablets USP, 10 mg, 25 mg and 50 mg contain the following inactive ingredients: anhydrous lactose, colloidal silicon dioxide, croscarmellose sodium, FD&C Yellow No. 6, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80 and titanium dioxide.

Hydroxyzine Hydrochloride Tablets USP, 25 mg and 50 mg also contain D&C Yellow No. 10 and FD&C Blue No. 2.

Both hydroxyzine and cetirizine act as antihistamines.
Dosage and direction

A whole daily dosage of 25-100 mg for adults should be divided into several intakes in general practice, in psychiatry daily dose maybe tripled. Usual duration of treatment is four weeks. Volume of the dosage should be diminished for aged persons and also in cases of kidney or liver failure. Do not use this drug unless it was prescribed by your doctor.

<b>Atarax Precautions</b>

If such side effects like drowsiness and weakness do not disappear after several days of treatment dosage of Hydroxyzine should be reduced. Avoid simultaneous intake with MAO inhibitors. It is cautiously prescribed for patients subjected to arrhythmia or taking anti-arrhythmic medications as well for patients predisposed to convulsions, sick with narrow-angle glaucoma, prostatic hypertrophy, hyperthyroidism. Avoid drinking alcohol during period of treatment with Hydroxyzine. Drivers and employers whose duties demand high concentration of attention should take the medication carefully in the process of their work.
<b>Contraindications</b>

Hypersensitivity, including one to cetirizine, aminophylline or ethylenediamine; porphyria; porphiria, pregnancy, during labor and delivery, breast-feeding.
Possible side effect from the use of Atarax (Hydroxyzine)

Emergency medical help is required if any of these signs of an allergy are found: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. The medication intake should interrupted. Other side effects may include: sedation, tiredness, sleepiness, dizziness, disturbed coordination, drying and thickening of oral and other respiratory secretions, and stomach distress, confusion, nervousness, irritability, blurred vision, double vision, tremor, loss of appetite, nausea.



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